The Merck Manual, first published in 1899, is the world’s best-selling medical book. Originally catering to health care professionals, it was re-edited in 1997 as The Merck Manual of Medical Information – Home Edition, using everyday language and trimming down technical information (like drug dosages). Its third edition was recently published as The Merck Manual Home Health Handbook; along with it, an iPhone/iPod Touch application (developed by Agile Partners) was released.

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